PDX Pharmaceuticals currently has an opening for a “Postdoctoral Researcher: Nanomedicine, Synthetic and Analytical Chemistry” position.
PDX Pharmaceuticals is seeking an outstanding Postdoctoral Researcher with experience in material science and analytical chemistry to join our pre-clinical research program. Experience in nanomedicine, nanoparticle synthesis, and rodent cancer models for drug candidate evaluation are big pluses.
This fellowship focuses on applied research into nanoparticle-based therapeutics for treating cancers and infectious diseases with movement towards clinical testing and applications. Our current focus is on siRNA therapeutics, vaccine, and novel cancer immunotherapy. The candidate will work on joint research projects between PDX Pharmaceuticals and Oregon Health & Science University (OHSU)’s department of Biomedical Engineering. Experience-based learning opportunities can be adapted to prepare a fellow for an academic or industry research career depending on the individual’s focus.
Applicants should be within 3 years of obtaining their PhD degree (with exception on a case-by-case basis).
· Develop and execute experiments to optimize the large-scale synthesis of and characterize PDX Pharma’s nanoparticle technology (polymer-coated inorganic nanoparticles).
· Work with Leadership Team to help plan and execute analytical and bioanalytic studies essential for IND application.
· Work with CDMO to establish process workflow and analytical method transfer of PDX Pharma’s nanoparticle manufacturing.
· Lead innovative projects that expand the scope and capabilities of the technology.
· Work in a highly collaborative and cross-functional team environment to execute experiments, analyze results, and communicate findings.
· Responsible for day-to-day research operation, including nanoparticle synthesis, batch experiments, analytical techniques, literature review, supervise RAs, and equipment maintenance.
· Take part in proposal grant writing and manuscripts.
· Keep current on new trends and technologies in nanomedicine and cancer research.
· PhD in chemistry, biochemistry, biomedical engineering, pharmaceutical science, or other related disciplines
· Experience in analytical chemistry techniques for inorganic compounds and polymers (e.g. HPLC, MS, ICP-MS, GPC, TGA, NMR, DLS, Nanosight)
· Experience in nanotechnology development for delivery of therapeutics (e.g., antibody, siRNA, mRNA, pDNA) and diagnostics (probes/sensors)
· Strong communication and interpersonal skills
· Detail-oriented, good record keeping, responsible, and willing to work flexible hours
· Good at teamwork and like to take on new initiatives and challenges
· Knowledge in nanomedicine
· Knowledge of the drug development pathway and FDA regulatory hurdles.
Job Type: Full-time
Salary for this position aligns with the NIH Scale but may be higher based on experience and skills.